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Peter B. Berger, MD

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Glenn N. Levine, MD

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WHAT'S NEW
Dynamic Slide Library
We introduce our Dynamic Slide Library with in-depth information on clinical trials, antiplatelet drugs, stents, antithrombotic agents, and acute coronary syndromes.

Identifying and Addressing Unmet Needs in Platelet Inhibition in Cardiology
This CME-certified webcast features 3 cardiologists on the Expert Panel of plateletNEWS.org presenting various aspects of antiplatelet therapy. The contemporary use of antiplatelet therapy in acute coronary syndrome patients and those who undergo percutaneous coronary interventions is discussed. There is also robust discussion about unmet clinical needs in the field and novel antiplatelet therapy and the agents that are on the horizon.

Welcome to My Practice
Step inside the practices of the plateletNEWS.org faculty members and see how they manage complex cases, research, and teaching. Now available: Christopher P. Cannon, MD, Frederic Scott Resnic, MD, Glenn N. Levine, MD, and Steven D. Wiviott, MD.

SLIDES OF THE MONTH

 
slide CURE: Primary Endpoint—MI/Stroke/Cardiovascular Death
Clopidogrel, in addition to aspirin (ASA) and other standard therapy, provided a 20% rel...

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slide CURE: Benefit of Clopidogrel Therapy at Various Time Intervals
Impact of clopidogrel vs placebo on cardiovascular death, myocardial infarction, or stro...

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slide CURE: Long-Term Results by Management Strategy
In this study of the CURE trial (N=12,562), clopidogrel (vs placebo) was found to be ben...

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slide CURE: Bleeding Episodes Through Follow-Up
In CURE, more major bleeding episodes occurred in the clopidogrel-plus-aspirin group t...

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slide Bivalirudin Angioplasty Trial (BAT) and Final Analysis
The original Bivalirudin Angioplasty Trial was conducted in 1995 and involved 4,098 pati...

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slide REPLACE-1: Treated Population
The REPLACE-1 trial randomized 1,056 patients undergoing elective or urgent revasculariz...

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slide REPLACE-2: Triple Ischemic Endpoint
REPLACE-2 randomized 6,010 patients undergoing urgent or elective percutaneous coronary ...

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slide REPLACE 2:Endpoints, 30 Days
The primary endpoint—30-day incidence of death, myocardial infarction, urgent reva...

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slide REPLACE 2 (PCI) and ACUITY (PCI Patients Only)
There are remarkable similarities between the results of REPLACE-2—a study of biva...

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slide PCI-CLARITY Meta-Analysis of Clopidogrel Pretreatment CV Death or MI After PCI, 30 Days
As part of the PCI-CLARITY study, the investigators performed a meta-analysis of PCI-CLARITY, ...

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slide CV Death, MI, or Stroke Following PCI
This meta-analysis of the PCI-cure, credo, and PCI-clarity trials included 6,325 patient...

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slide ISAR-REACT: Results, 30 Days
The ISAR-REACT trial randomized 2,159 patients who underwent percutaneous coronary inter...

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slide ISAR-REACT: Death or MI, 12 Months
A subsequent analysis of the ISAR-REACT trial followed patients to 12 months after randomizati...

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slide ISAR-SWEET: Adverse Events, 30 Days
The ISAR-SWEET trial randomized 701 diabetic patients with coronary artery disease who u...

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slide ISAR-REACT 2: Efficacy Analysis
The ISAR-REACT 2 trial randomized 2,022 patients with non−ST-segment elevation acu...

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slide ACUITY: Death, MI, Target Vessel Revascularization
The ACUITY trial randomized 13,819 patients with acute coronary intervention to receive ...

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slide Time Course of Platelet Inhibition After Different Clopidogrel Loading Doses
More intense and rapid platelet inhibition (PI) can be achieved with loading doses of cl...

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slide Persistent Platelet Inhibition Variability With Increasing Clopidogrel Loading Dose
This study compared the degree of platelet inhibition (PI) and the time course of functional r...

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slide Out-of-Hospital 6-Month Post-PCI Outcomes Stratified by Reactivity in Patients on Consistent Clopidogrel Therapy
This study sought to determine whether platelet reactivity during clopidogrel therapy&md...

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slide Frequency Distribution of Platelet Inhibition After Cessation of Daily Clopidogrel Therapy
This study compared the degree of platelet inhibition (PI) and the time course of functional r...

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slide Time Course of Platelet Recovery After a Single Clopidogrel 600-mg Dose
This slide shows individual responses with regard to platelet inhibition to a single 600...

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slide Triple Antiplatelet Therapy in Patients With Acute MI Undergoing PCI
Dual antiplatelet therapy (DAT) with aspirin and clopidogrel has been shown to improve clinica...

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slide HORIZONS AMI: Impact of Clopidogrel Loading Dose on Efficacy of Bivalirudin
In the HORIZONS AMI trial, bivalirudin (BV) was compared with unfractionated heparin + glycopr...

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slide Adjustment of Clopidogrel Loading Dose Using the VASP Index: Effects on MACE
Resistance to clopidogrel is correlated with worse outcome following percutaneous corona...

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slide TRITON-TIMI 38: Intensive Antiplatelet Therapy and Rates of Thrombosis
The results of the TRITON-TIMI 38 trial show that prasugrel can reduce ischemic events c...

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slide TRITON-TIMI 38: Intensive Antiplatelet Therapy and Rates of Thrombosis
The results of the TRITON-TIMI 38 trial show that prasugrel can reduce ischemic events compare...

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slide TRITON-TIMI 38: Intensive Antiplatelet Therapy and Rates of Thrombosis
The results of the TRITON-TIMI 38 trial show that prasugrel can reduce ischemic events compare...

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slide TRITON-TIMI 38: Subgroup Analysis of Antiplatelet Therapy Effect on Thrombosis
The results of the TRITON-TIMI 38 trial show that prasugrel can reduce ischemic events compare...

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IN THE NEWS

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Copyright 2008 Medical News Today
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